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Valspodar Catalog No.:M8136-2 PubMed PMID: 27283322

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Description

PubMed PMID: 27283322

Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based DrugDesign

that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1

19R)-13-((1H-indol-3-yl)methyl)-19-((R)-2-amino-3-phenylpropanamido)-10-(4-aminobutyl)-16-benzyl-N-((2R

Smiles: CNC(=O)CN1CC(=O)O[Gd]2OC(=O)CN(CCN(CC(=O)NC)CC(=O)O2)CC1

Valspodar Catalog No.:M8136-2 PubMed PMID: 27283322Valspodar, also known as PSC 833, is an analogue of cyclosporin A. Valspodar inhibits p glycoprotein, the multidrug resistance efflux pump, thereby restoring the retention and activity of some drugs in some drug resistant tumor cells. This agent also induces caspase mediated apoptosis. Product information CAS Number: 121584 18 7 Molecular Weight: 1214. 62 Formula: C63H111N11O12 Synonym: PSC 833 PSC 833 PSC833 Chemical Name:

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